Provider review
Signos review
Early cancellation on the 3- or 6-month plan can carry a fee, no proration
$199 a month bundles the medication with a Dexcom Stelo continuous glucose sensor and a coaching app, on a three- or six-month term. Cancel early and there may be a fee with no proration — and which drug you get is decided after intake.
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On this page
The verdict
Signos' core differentiator is real and genuinely useful — a named, FDA-cleared CGM (Stelo by Dexcom) bundled with the medication, giving you glucose feedback most GLP-1 telehealth programs don't offer. But the $199/mo price assumes you complete the full 3- or 6-month term; canceling early can trigger a fee with no prorated refund, and you won't know in advance which GLP-1 drug you'll actually be prescribed since the site never names one before you sign up.
Signos is not ranked on any of our rankings. This is a standalone read of what the company publishes about itself — the providers we do rank in this category are on our semaglutide provider ranking. Nothing on this page is a performance claim — see the evidence review for what these compounds do and do not do.
Who it is for, and who it is not
A good fit if
- You want a continuous glucose monitor bundled with your GLP-1 program, not sold separately
- You're comfortable committing to the full 3- or 6-month term to avoid a cancellation fee
- You want app-based coaching and real-time glucose data alongside medication
Look elsewhere if
- You want to know upfront whether you'll get semaglutide or tirzepatide — the site doesn't specify before signup
- You want to cancel mid-term without risking a fee or losing a prorated refund
- You want a named compounding pharmacy rather than general "certified U.S. pharmacies" language
What it actually costs
What they advertise
Signos+ plan: $199/month on signos.com/plans.
What you actually pay, month to month
$199/month applies across the 3- or 6-month term; early cancellation may carry a fee with no proration.
The commitment trap
The $199/mo price assumes completing the full term; canceling early can trigger a fee, and refunds aren't prorated.
Checked live on Signos's own site at https://www.signos.com/plans?plan=glp in August 2026. Prices change without notice — confirm before you buy. Work out what a vial actually gives you with our peptide dose calculator.
What is included
The cheapest headline number in this category is often the one with the least attached to it. Here is what Signos bundles in, and what it does not.
Clinician consult
Provider prescription through OpenLoop Health or an independent clinician network.
Bloodwork / labs
Not published.
Follow-ups and dose changes
No cadence published.
Human support
Dietitian access and app coaching.
Injection supplies
Stelo biosensor CGM by Dexcom included at no extra cost.
Shipping
Free rapid shipping.
Pharmacy, labs and oversight
The pharmacy
Described only as "certified U.S. pharmacies"; no specific name disclosed.
Oversight
No cadence published.
Compounded peptides are not FDA-approved products, and a 503A pharmacy compounds for a named patient while a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Our guide to verifying a certificate of analysis covers what to ask for.
Where you can get it
Not published anywhere.
The honest cons
The part they would rather you skipped
Signos' own FAQ states early cancellations on the 3- or 6-month plan "may be subject to a cancellation fee" with no prorated refund — worth knowing before you sign up, since the $199/mo headline price assumes you finish the full term.
- Early cancellation may carry a fee with no prorated refund
- Neither semaglutide nor tirzepatide is named before signup — the drug is provider-determined post-intake
- Compounding pharmacy never individually named
- State coverage not published anywhere on the site
None of this is unique to Signos — the whole category shares it. What we hold against a provider is the part it hides, and the ways vendors hide things are cataloged in our vendor red-flags guide.
How it compares
The providers we rank on our semaglutide provider ranking, in the order that ranking ranks them. Signos is not among them: it is reviewed here, not ranked there, and we would rather show you the comparison than pretend the two are the same thing.
- COCollectiveThe cheapest medication price here, on a membership the headline omits
- CoreAge RxOne price that does not move when your dose does
- BHBodybuilding Health+The deep peptide catalog is gone; the GLP-1 pricing got better
- RxSpan MDOral tablet only, at a real $179 monthly rate
- Enhance MDWrites a flat-price-at-every-dose policy down — and charges near the top for it
- Found HealthInsurance-integrated, unlike every cash-only compounder here — but $99 needs a prepay
- Direct MedsThe plainest price mechanics on either ranking, from a company with an FDA warning letter
- Synergy RxPublishes a starting number, and nothing about what it commits you to
13 more providers rank on our semaglutide provider ranking — see the full ranking. Every provider we review →
Read this before you buy
A provider comparison is half the decision. The other half is whether the compound does anything for you at all — and whether it is allowed where you compete. Growth-hormone secretagogues are banned in tested sport, year-round, and a prescription does not change that.
Facts on this page reflect Signos's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Signos's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved, and growth-hormone secretagogues are banned in tested sport year-round. See our disclosure and editorial policy.