Provider review
Silhouette MD review
Names a real clinical partner, OpenLoop Health — tirzepatide runs above many rivals
Silhouette MD is a concierge-style GLP-1 telehealth provider offering compounded semaglutide and tirzepatide in both injectable and oral forms, with prescriptions issued and fulfilled through a named, established clinical partner, OpenLoop Health, per prior directory research not independently reconfirmed on this pass after the site returned HTTP 403 to every fetch attempt. Pricing is described as transparent and published: semaglutide injection starts at $149/mo, but tirzepatide runs $299/mo and oral options run $263 to $325/mo — above many compounded competitors on this board. Every plan includes provider oversight, monitoring, and check-ins as part of the concierge model. But state availability isn't published, and it's a newer brand with a limited independent review history.
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On this page
The verdict
Silhouette MD names a real, checkable clinical backbone — OpenLoop Health, an established telehealth network already documented behind several other reviews on this site — and publishes transparent pricing starting at $149/mo for semaglutide injection, with concierge-level monitoring and check-ins bundled into every plan, per prior directory research. The tradeoff: tirzepatide ($299/mo) and the oral options ($263-$325/mo) both price above many compounded competitors here, state availability isn't published, and it's a newer brand without much independent review history yet. This review rests on that prior research rather than a fresh site check, since silhouette-md.com returned HTTP 403 to every fetch attempt this pass.
Silhouette MD is not ranked on any of our boards. This is a standalone read of what the company publishes about itself — the providers we do rank in this category are on our semaglutide provider ranking. Nothing on this page is a performance claim — see the evidence review for what these compounds do and do not do.
Who it is for, and who it is not
A good fit if
- You want a named, established clinical network (OpenLoop Health) behind your prescription rather than an unnamed backend
- You want both injectable and oral compounded options from one provider
- You want concierge-level monitoring and check-ins bundled into every plan
Look elsewhere if
- You want tirzepatide or an oral option at a price competitive with the cheaper compounded providers on this board
- You want your state's availability confirmed before signing up
- You want an established brand with a longer independent review history
What it actually costs
What they advertise
Compounded semaglutide injection from $149/mo, per prior directory research (site returned HTTP 403 on this pass).
What you actually pay, month to month
$149/mo is the published semaglutide injection rate; tirzepatide runs $299/mo and oral options $263-$325/mo, per prior research.
Checked live on Silhouette MD's own site at https://silhouette-md.com/ in August 2026. Prices change without notice — confirm before you buy. Work out what a vial actually gives you with our peptide dose calculator.
What is included
The cheapest headline number in this category is often the one with the least attached to it. Here is what Silhouette MD bundles in, and what it does not.
Clinician consult
Provider oversight bundled into every plan, per prior research.
Bloodwork / labs
Not addressed in the sources read.
Follow-ups and dose changes
Ongoing monitoring and check-ins bundled into every plan, per…
prior research.
Human support
Concierge-level guidance and check-ins, per prior research.
Injection supplies
Not itemized in the sources read.
Shipping
Not addressed with specific terms in the sources read.
Pharmacy, labs and oversight
The pharmacy
Prescriptions issued and fulfilled through OpenLoop Health, a named clinical partner, per prior research.
Oversight
Provider oversight bundled into every plan, per prior research. Ongoing monitoring and check-ins bundled into every plan, per prior research.
Compounded peptides are not FDA-approved products, and a 503A pharmacy compounds for a named patient while a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Our guide to verifying a certificate of analysis covers what to ask for.
Where you can get it
Not published, per prior research.
The honest cons
The part they would rather you skipped
Silhouette MD names a real clinical partner, OpenLoop Health, and publishes a competitive semaglutide entry price — but tirzepatide and the oral options both run above many compounded competitors on this board, and as a newer brand it doesn't yet have much independent review history to weigh against that higher price.
- Tirzepatide ($299/mo) and oral options ($263-$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Site returned HTTP 403 to every fetch attempt this pass — claims rest on prior research, not a fresh check
None of this is unique to Silhouette MD — the whole category shares it. What we hold against a provider is the part it hides, and the ways vendors hide things are catalogued in our vendor red-flags guide.
How it compares
The providers we rank on our semaglutide provider ranking, in the order that board ranks them. Silhouette MD is not among them: it is reviewed here, not ranked there, and we would rather show you the comparison than pretend the two are the same thing.
- BHBodybuilding Health+One of the deepest peptide catalogues here, and the loosest one
- Enhance MDWrites a flat-price-at-every-dose policy down — and charges near the top for it
- RxSpan MDOral tablet only, at a real $179 monthly rate
- Direct MedsThe plainest price mechanics on either board, from a company with an FDA warning letter
- Synergy RxPublishes a starting number, and nothing about what it commits you to
- Sprout HealthA $150 markdown the site never explains, and a semaglutide price quoted by the quarter
- Strut HealthInjection or troche, but $119 is the auto-refill price only
- MadeMedPrices are published — but there is no monthly option at all
7 more providers rank on our semaglutide provider ranking — see the full ranking. Every provider we review →
Read this before you buy
A provider comparison is half the decision. The other half is whether the compound does anything for you at all — and whether it is allowed where you compete. Growth-hormone secretagogues are banned in tested sport, year-round, and a prescription does not change that.
Facts on this page reflect Silhouette MD's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Silhouette MD's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved, and growth-hormone secretagogues are banned in tested sport year-round. See our disclosure and editorial policy.