Provider review
Silhouette MD review
Names a real clinical partner, OpenLoop Health — tirzepatide runs above many rivals
Semaglutide injections start at $149 a month, but tirzepatide is $299 and the oral options $263 to $325 — above most compounded rivals. Prescribing runs through OpenLoop Health, and its served states are never published.
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On this page
The verdict
Silhouette MD names a real, checkable clinical backbone — OpenLoop Health, an established telehealth network already documented behind several other reviews on this site — and publishes transparent pricing starting at $149/mo for semaglutide injection, with concierge-level monitoring and check-ins bundled into every plan, at our last check. The tradeoff: tirzepatide ($299/mo) and the oral options ($263-$325/mo) both price above many compounded competitors here, state availability isn't published, and it's a newer brand without much independent review history yet. This rests on our last check rather than a fresh read, since silhouette-md.com blocked every automated check.
Silhouette MD is not ranked on any of our rankings. This is a standalone read of what the company publishes about itself — the providers we do rank in this category are on our semaglutide provider ranking. Nothing on this page is a performance claim — see the evidence review for what these compounds do and do not do.
Who it is for, and who it is not
A good fit if
- You want a named, established clinical network (OpenLoop Health) behind your prescription rather than an unnamed backend
- You want both injectable and oral compounded options from one provider
- You want concierge-level monitoring and check-ins bundled into every plan
Look elsewhere if
- You want tirzepatide or an oral option at a price competitive with the cheaper compounded providers here
- You want your state's availability confirmed before signing up
- You want an established brand with a longer independent review history
What it actually costs
What they advertise
Compounded semaglutide injection from $149/mo, the site blocks automated checks, so this is from our last look.
What you actually pay, month to month
$149/mo is the published semaglutide injection rate; tirzepatide runs $299/mo and oral options $263-$325/mo, at our last check.
Checked live on Silhouette MD's own site at https://silhouette-md.com/ in August 2026. Prices change without notice — confirm before you buy. Work out what a vial actually gives you with our peptide dose calculator.
What is included
The cheapest headline number in this category is often the one with the least attached to it. Here is what Silhouette MD bundles in, and what it does not.
Clinician consult
Provider oversight bundled into every plan, at our last check.
Bloodwork / labs
Not published.
Follow-ups and dose changes
Ongoing monitoring and check-ins bundled into every plan
at our last check.
Human support
Concierge-level guidance and check-ins, at our last check.
Injection supplies
Not itemized.
Shipping
No terms published.
Pharmacy, labs and oversight
The pharmacy
Prescriptions issued and fulfilled through OpenLoop Health, a named clinical partner, at our last check.
Oversight
Ongoing monitoring and check-ins bundled into every plan, at our last check.
Compounded peptides are not FDA-approved products, and a 503A pharmacy compounds for a named patient while a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Our guide to verifying a certificate of analysis covers what to ask for.
Where you can get it
Not published, at our last check.
The honest cons
The part they would rather you skipped
Silhouette MD names a real clinical partner, OpenLoop Health, and publishes a competitive semaglutide entry price — but tirzepatide and the oral options both run above many compounded competitors here, and as a newer brand it doesn't yet have much independent review history to weigh against that higher price.
- Tirzepatide ($299/mo) and oral options ($263-$325/mo) priced above many compounded competitors
- State availability not published
- Newer brand with limited independent review history
- Site blocked every automated check — claims rest on our last check rather than a fresh one
None of this is unique to Silhouette MD — the whole category shares it. What we hold against a provider is the part it hides, and the ways vendors hide things are cataloged in our vendor red-flags guide.
How it compares
The providers we rank on our semaglutide provider ranking, in the order that ranking ranks them. Silhouette MD is not among them: it is reviewed here, not ranked there, and we would rather show you the comparison than pretend the two are the same thing.
- COCollectiveThe cheapest medication price here, on a membership the headline omits
- CoreAge RxOne price that does not move when your dose does
- BHBodybuilding Health+The deep peptide catalog is gone; the GLP-1 pricing got better
- RxSpan MDOral tablet only, at a real $179 monthly rate
- Enhance MDWrites a flat-price-at-every-dose policy down — and charges near the top for it
- Found HealthInsurance-integrated, unlike every cash-only compounder here — but $99 needs a prepay
- Direct MedsThe plainest price mechanics on either ranking, from a company with an FDA warning letter
- Synergy RxPublishes a starting number, and nothing about what it commits you to
13 more providers rank on our semaglutide provider ranking — see the full ranking. Every provider we review →
Read this before you buy
A provider comparison is half the decision. The other half is whether the compound does anything for you at all — and whether it is allowed where you compete. Growth-hormone secretagogues are banned in tested sport, year-round, and a prescription does not change that.
Facts on this page reflect Silhouette MD's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Silhouette MD's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved, and growth-hormone secretagogues are banned in tested sport year-round. See our disclosure and editorial policy.