Provider review
Primary Clinic review
Charges for the care and the drug separately, and admits it
$89 a month buys unlimited primary care, routine labs and direct messaging — and no medication at all; the compounded GLP-1 sits on top of it, from $85 to $183 a month as the dose climbs.
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On this page
The verdict
Primary Clinic is not really a GLP-1 platform. It is a direct-primary-care membership at $89 a month — unlimited visits, unlimited provider messaging, an annual blood panel and routine medications — that also sells compounded semaglutide and tirzepatide to its own members at what it calls wholesale. That structure is unusually honest and unusually awkward at the same time. Honest, because the clinic publishes a dose-by-dose price table instead of one flattering headline, and answers the obvious question in its own FAQ: "Is the medication cost included in the $89 membership fee? No." Awkward, because there is no single number to compare with anything else on this site. Month one is $174 for semaglutide. At a 2.25-2.7 mg maintenance dose it is $272, and tirzepatide at 8-10 mg is $347. Both figures are real and both are published — but only after you have understood that the bill always has two lines.
Primary Clinic is not ranked on any of our boards. This is a standalone read of what the company publishes about itself — the providers we do rank in this category are on our semaglutide provider ranking. Nothing on this page is a performance claim — see the evidence review for what these compounds do and do not do.
Who it is for, and who it is not
A good fit if
- You want a primary-care relationship rather than a refill service, and would use the visits
- You want to see the price at your maintenance dose, not only at the starting dose
- You live in one of the eighteen jurisdictions it names on the site
Look elsewhere if
- You only want the drug — the $89 recurs whether or not you fill a prescription
- You want one number to compare against a flat-rate seller
- You want the medication price before you join: the wholesale table is member-only
- You need a named compounding facility rather than a category
What it actually costs
What they advertise
A published dose-by-dose table: semaglutide $85/month at 0.25-0.75 mg, $108 at 1-1.25 mg, $145 at 1.5-2 mg and $183 at 2.25-2.7 mg; tirzepatide $133, $183, $233 and $258 across its four bands. Separately, an $89/month membership.
What you actually pay, month to month
$174 in month one for semaglutide ($85 medication + $89 membership), rising to $272 once the dose reaches the top published band. Tirzepatide starts at $222 and reaches $347. Neither published number is the monthly cost on its own.
The commitment trap
Two required charges the site never adds together. The $89 membership is mandatory, recurs whether or not a prescription is filled, and buys no medication — the clinic's own FAQ says exactly that — while the medication line more than doubles across the dose ladder underneath it.
Money you will meet later
- The $89 membership continues in any month you do not order medication
- Medications "outside of the formulary or requiring special handling may be subject to additional charges"
- Labs are covered, but members travel to a designated lab facility to have them drawn
- The wholesale price table is available "only to active Primary Clinic DPC members"
Checked live on Primary Clinic's own site at https://directglp1.com/ in August 2026. Prices change without notice — confirm before you buy. Work out what a vial actually gives you with our peptide dose calculator.
What is included
The cheapest headline number in this category is often the one with the least attached to it. Here is what Primary Clinic bundles in, and what it does not.
Clinician consult
A free virtual consult by phone or text comes first, then the…
$89 membership covers unlimited primary-care visits and direct provider messaging through a Charm EHR patient portal.
Bloodwork / labs
Genuinely included, with one caveat worth reading: the…
membership covers an annual comprehensive blood panel plus further lab work as medically indicated, but the agreement makes members responsible for travelling to a designated lab facility.
Follow-ups and dose changes
Unlimited visits and unlimited secure messaging sit inside the…
membership, so a dose change is ordinary care rather than a billable event.
Human support
A continuing provider relationship rather than whoever is on…
shift — the clinic sells continuity as the product. No coach or dietitian is advertised.
Injection supplies
Not published
Neither the site nor the intake says whether syringes and alcohol swabs come with the vial.
Shipping
Medication "ships straight to your door"
No cost and no timeframe is published.
Pharmacy, labs and oversight
The pharmacy
Names the category, not the facility: "compounded tirzepatide and semaglutide from licensed 503A pharmacies at wholesale pricing", with a footnote that compounded medications are "not affiliated with brand-name GLP-1 drugs". Saying 503A out loud puts it ahead of most of this category — but an unnamed pharmacy still cannot be looked up.
Oversight
A free virtual consult by phone or text comes first, then the $89 membership covers unlimited primary-care visits and direct provider messaging through a Charm EHR patient portal. Unlimited visits and unlimited secure messaging sit inside the membership, so a dose change is ordinary care rather than a billable event.
Compounded peptides are not FDA-approved products, and a 503A pharmacy compounds for a named patient while a 503B outsourcing facility manufactures in batches under CGMP. Neither is a quality guarantee on its own — a named facility is simply a fact you can check, and an unnamed “partner pharmacy network” is not. Our guide to verifying a certificate of analysis covers what to ask for.
Where you can get it
Eighteen jurisdictions, published by name: AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA and WA — seventeen states plus the District of Columbia — with "additional states coming soon".
The honest cons
The part they would rather you skipped
You cannot see what the medication costs until you have paid to join. The wholesale table is labelled "available only to active Primary Clinic DPC members", and the $89 that unlocks it buys no medication at all, so the cheapest way to find out whether Primary Clinic is cheap is to become a member first. The second thing the headline hides is the ladder: the semaglutide line more than doubles from $85 to $183 between the starting band and the maintenance band, and the tirzepatide line runs from $133 to $258, so a reader who budgets from the entry figure will be wrong by hundreds of dollars a year before the membership is even counted.
- The $89 membership is required, recurs monthly, and includes no medication
- Medication price climbs across four dose bands on both molecules
- The wholesale price table is gated to active members
- Eighteen jurisdictions only — a national platform this is not
- No compounding facility named, only the 503A category
- Nothing published about injection supplies, shipping cost or delivery time
- The public HTML carries no price at all: every figure above is rendered by JavaScript
None of this is unique to Primary Clinic — the whole category shares it. What we hold against a provider is the part it hides, and the ways vendors hide things are catalogued in our vendor red-flags guide.
How it compares
The providers we rank on our semaglutide provider ranking, in the order that board ranks them. Primary Clinic is not among them: it is reviewed here, not ranked there, and we would rather show you the comparison than pretend the two are the same thing.
- BHBodybuilding Health+One of the deepest peptide catalogues here, and the loosest one
- Enhance MDWrites a flat-price-at-every-dose policy down — and charges near the top for it
- RxSpan MDOral tablet only, at a real $179 monthly rate
- Direct MedsThe plainest price mechanics on either board, from a company with an FDA warning letter
- Synergy RxPublishes a starting number, and nothing about what it commits you to
- Sprout HealthA $150 markdown the site never explains, and a semaglutide price quoted by the quarter
- Strut HealthInjection or troche, but $119 is the auto-refill price only
- MadeMedPrices are published — but there is no monthly option at all
7 more providers rank on our semaglutide provider ranking — see the full ranking. Every provider we review →
Read this before you buy
A provider comparison is half the decision. The other half is whether the compound does anything for you at all — and whether it is allowed where you compete. Growth-hormone secretagogues are banned in tested sport, year-round, and a prescription does not change that.
Facts on this page reflect Primary Clinic's own public disclosures when we last checked them, in August 2026. Prices and terms change without notice — confirm on Primary Clinic's site before you buy. Provider names and logos on this page identify the company under review; their use does not imply endorsement, sponsorship or affiliation. This page is informational and not medical advice; compounded peptides are not FDA-approved, and growth-hormone secretagogues are banned in tested sport year-round. See our disclosure and editorial policy.