Compound guide · Metabolic & GLP-1
MOTS-c: what it is, its legal status and the evidence
A mitochondrial-derived peptide sold for endurance and metabolic health.
What the evidence shows
Evidence is preclinical; no controlled human endurance-performance trial exists.
Read the full review: MOTS-c: The "Exercise Mimetic" Peptide — Does It Work?
Legal and FDA status
No lawful compounding route today. MOTS-c is sold to athletes for endurance and mitochondrial performance; FDA evaluated it for obesity and osteoporosis, and recorded that it had identified no human exposure data for it by any route.
Anti-doping status
MOTS-c is not named individually on the WADA list. That is not a clearance: check the live list before competing.
Read next: every MOTS-c guide
What the evidence says
Dosage and how it's taken
Legal and FDA status
Is there a legal way to get it?
Not lawful to compound, so we list no sellers of MOTS-c.
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.